Preparation of (S)-N-Boc-5-oxaproline
نویسندگان
چکیده
منابع مشابه
On the rearrangement of N-aryl-N-Boc-phosphoramidates to N-Boc-protected o-aminoarylphosphonates
Abstract Various arylamines were converted in two steps to N-Boc-N-arylphosphoramidates. LiTMP and LDA induced directed ortho-metalation at temperatures from -78 to 0 °C. The ensuing [1,3]-migration of the phosphorus atom with its substituents from the nitrogen to the ortho-carbanionic carbon atom gave N-Boc-protected o-aminoarylphosphonates. The nature of the substituent of 3-substituted pheny...
متن کاملNew Unambiguous Boc(n,n) Tracking Technique
Galileo and Modernized GPS have included in their signal structures a new signal modulation: the Binary Offset Carrier (BOC). In the navigation field, this modulation is characterized by the chipping rate of its spreading code (m×1.023 MHz) and the frequency of its square sub-carrier (n×1.023 MHz). As a consequence, it is usually referred to as a BOC(n,m) modulation. The choice of the parameter...
متن کاملDynamic resolution of N-Boc-2-lithiopiperidine.
Dynamic thermodynamic resolution of N-Boc-2-lithiopiperidine is possible using a chiral ligand; the two enantiomers of this organolithium can be resolved with selectivities of up to 85 : 15 from a selection of 26 chiral diamino-alkoxide ligands screened.
متن کاملReactivity series for s-BuLi/diamine-mediated lithiation of N-Boc pyrrolidine: applications in catalysis and lithiation of N-Boc piperidine.
Using competition experiments between a range of ligands and (-)-sparteine, a reactivity series for N-Boc pyrrolidine lithiation using s-BuLi/diamines has been constructed; the results indicate that the s-BuLi/(+)-sparteine surrogate complex is more reactive than s-BuLi/(-)-sparteine and this has been exploited in the selection of ligand pairs for ligand exchange catalytic asymmetric lithiation...
متن کاملMitsunobu dehydration of N-Boc neomycin B.
Reaction of hexa-N-Boc neomycin B with TPP and DIAD in toluene results in the formation of an epoxide in ring IV, not an aziridine or azetidine as previously reported.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Organic Syntheses
سال: 2018
ISSN: 2333-3553
DOI: 10.15227/orgsyn.095.0157